NCLEX Review about Immune System Disorders 41-45

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41. A nurse is monitoring a client with herpes simplex virus who is receiving intravenous (IV) acyclovir (Zovorax). Which of the following laboratory results would be of concern as a possible adverse effect of this medication?

a) blood urea nitrogen (BUN) of 36 mg/dL
b) platelet count of 300,000 cells/mm3
c) white blood cell count of 6000 cells/mm3
d) red blood cell count of 5.2 million cells/mm3

42. A client with acquired immunodeficiency syndrome (AIDS) is receiving ganciclovor (Cytovene). The nurse takes which priority nursing action in caring for this client?

a) ensuring that the client uses an electric razor for shaving
b) administering the medication with an antacid
c) monitoring for signs of hyperglycemia
d) administering the medication without food

43. A client with acquired immunodeficiency syndrome (AIDS) has been started on therapy with zidovudine also called azidothymidine (AZT)(Retrovir). The nurse monitors the results of which laboratory blood study for adverse effects of therapy?

a) complete blood count (CBC)
b) blood urea nitrogen (BUN) level
c) creatinine level
d) potassium concentration

44. A client with acquired immunodeficiency syndrome (AIDS) is receiving didanosine (Videx). The nurse reviewing the client's laboratory results should most closely monitor serum levels of:

a) cholesterol
b) amylase
c) glucose
d) protein

45. A client is receiving zalcitabine (Hivid). The nurse plans to monitor the results of which study to determine the effectiveness of this medication?

a) enzyme-linked immunosorbent assay (ELISA)
b) western blot
c) CD4+ cell count
d) complete blood cell (CBC) count with differential





NCLEX Review about Immune System Disorders:
ANSWERS AND RATIONALE

41) A
- Although the most common adverse reactions with this medication are phlebitis and inflammation at the IV site, reversible nephrotoxicity evidenced by an elevated serum creatinine and BUN levels can occur in some clients. The cause of nephrotoxicity is deposition of acyclovir in the renal tubules. The risk of renal injury is increased by dehydration and by the use of other nephrotoxic medications. The values identified in options B, C, and D are within normal limits.

42) A
- Because ganciclovir causes neutropenia and thrombocytopenia as the most frequent side effects, the nurse monitors for signs and symptoms of bleeding and implements the same precautions as for a client receiving anticoagulant therapy. The medication does not have to be taken on an empty stomach or without food and should not be taken with an antacid. The medication may cause hypoglycemia, but not hyperglycemia.

43) A
- Common adverse effects of this medication are agranulocytopenia and anemia. The nurse monitors the CBC results for these changes. BUN, creatinine, and potassium are unrelated to this medication.

44) B
- This medication is toxic to both the pancreas and the liver. A serum amylase level that is increased 1.5 to 2 times normal may signify pancreatitis and may be potentially fatal in the client with AIDS. Therefore, the nurse monitors the results of amylase and liver function studies closely. Options A, C, and D are unrelated to this medication.

45) C
- Zalcitabine slows the progression of acquired immunodeficiency syndrome (AIDS) by improving the CD4+ cell count. A CBC with differential may be done as part of an ongoing monitoring of the status of the client with AIDS, and to detect adverse effects of other medications. The ELISA and the Western blot are performed to diagnose AIDS initially.


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NCLEX Review about Immune System Disorders (1-5)


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NCLEX Review about Immune System Disorders (46-50)

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